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1. (WO2016086197) METHOD OF IDENTIFYING AND TREATING A PERSON HAVING A PREDISPOSITION TO OR AFFLICTED WITH A CARDIOMETABOLIC DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/086197    International Application No.:    PCT/US2015/062787
Publication Date: 02.06.2016 International Filing Date: 25.11.2015
IPC:
C12Q 1/68 (2006.01)
Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC. [US/US]; 75 Francis Street Boston, MA 02115 (US).
THE GENERAL HOSPITAL CORPORATION [US/US]; (US)
Inventors: EBERT, Benjamin, Levine; (US).
JAISWAL, Siddhartha; (US).
KATHIRESAN, Sekar; (US)
Agent: KOWALSKI, Thomas, J.; (US)
Priority Data:
62/084,127 25.11.2014 US
Title (EN) METHOD OF IDENTIFYING AND TREATING A PERSON HAVING A PREDISPOSITION TO OR AFFLICTED WITH A CARDIOMETABOLIC DISEASE
(FR) MÉTHODE D'IDENTIFICATION ET DE TRAITEMENT D'UNE PERSONNE PRÉSENTANT UNE PRÉDISPOSITION À SOUFFRIR OU SOUFFRANT D'UNE MALADIE CARDIOMÉTABOLIQUE
Abstract: front page image
(EN)The invention relates to method for identifying and selecting a subject with increased risk of developing a cardiometabolic disease and optionally, providing a personalized medicine method, which may involve sequencing at least part of a genome of one or more cells in a blood sample of the subject and identifying from said sequencing one or more mutations in one or more somatic mutations.
(FR)L'invention concerne un procédé permettant d'identifier et de sélectionner un sujet présentant un risque accru de développer une maladie cardiométabolique et, éventuellement, de lui proposer un traitement médical personnalisé, ce qui peut impliquer le séquençage d'au moins une partie du génome d'une ou plusieurs cellules présentes dans un échantillon de sang du sujet et l'identification, sur la base dudit séquençage, d'une ou de plusieurs mutations parmi une ou plusieurs mutations somatiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)