WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016086088) WOUND HEALING THROUGH SIRT1 OVEREXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/086088    International Application No.:    PCT/US2015/062588
Publication Date: 02.06.2016 International Filing Date: 25.11.2015
IPC:
C07K 14/47 (2006.01)
Applicants: NORTHWESTERN UNIVERSITY [US/US]; 633 Clark Street Evanston, Illinois 60208 (US)
Inventors: AMEER, Guillermo A.; (US).
JEN, Michele; (US)
Agent: STAPLE, David W.; (US)
Priority Data:
62/084,375 25.11.2014 US
Title (EN) WOUND HEALING THROUGH SIRT1 OVEREXPRESSION
(FR) CICATRISATION PAR SUREXPRESSION DE SIRT1
Abstract: front page image
(EN)Compositions and methods are provided for improved wound healing. In particular, provided herein are compositions and methods for the direct delivery of Sirtuin-1 (Sirtl) or vectors encoding Sirtl to the wounds (e.g., of diabetic patients). In some embodiments, provided herein are therapeutic devices comprising: (a) a vector encoding Sirtuin-1 (Sirt 1); and (b) a hydrogel carrier. In some embodiments, the vector comprises a viral vector comprising a polynucleotide sequence encoding Sirt 1. In some embodiments, the vector comprises a non-viral vector comprising a polynucleotide sequence encoding Sirtl.
(FR)L'invention concerne des compositions et des méthodes permettant d'améliorer la cicatrisation. En particulier, l'invention concerne des compositions et des méthodes pour l'administration directe de sirtuine 1 (Sirt1) ou de vecteurs codant pour Sirt1 sur les plaies (par exemple, de patients diabétiques).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)