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1. (WO2016085967) METHODS OF TREATING CANCER BY TARGETING TUMOR-ASSOCIATED MACROPHAGES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/085967    International Application No.:    PCT/US2015/062395
Publication Date: 02.06.2016 International Filing Date: 24.11.2015
IPC:
A61K 47/48 (2006.01)
Applicants: ENDOCYTE, INC. [US/US]; 3000 Kent Avenue West Lafayette, Indiana 47906 (US).
PURDUE RESEARCH FOUNDATION [US/US]; 1801 Newman Road West Lafayette, Indiana 47906 (US)
Inventors: LU, Yingjuan J.; (US).
WHEELER, II, Leroy W.; (US).
LOW, Philip Stewart; (US).
LEAMON, Christopher P.; (US)
Agent: BALL, Rebecca L.; (US)
Priority Data:
62/084,194 25.11.2014 US
62/149,067 17.04.2015 US
Title (EN) METHODS OF TREATING CANCER BY TARGETING TUMOR-ASSOCIATED MACROPHAGES
(FR) PROCÉDÉS DE TRAITEMENT DU CANCER PAR CIBLAGE DE MACROPHAGES ASSOCIÉS À UNE TUMEUR
Abstract: front page image
(EN)Methods for treating cancers using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker are described. Methods for treating cancers using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker to target tumor associated macrophages are described.
(FR)L'invention concerne des procédés de traitement de cancers au moyen d'un ou de plusieurs composés comprenant un ligand se liant au récepteur du folate attaché à un médicament par l'intermédiaire d'un lieur. L'invention concerne également des procédés de traitement de cancers au moyen d'un ou de plusieurs composés comprenant un ligand se liant au récepteur du folate attaché à un médicament par l'intermédiaire d'un lieur pour cibler des macrophages associés à une tumeur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)