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1. (WO2016085208) SFRP5-DERIVED PEPTIDE FRAGMENT AND COSMETIC COMPOSITION FOR SKIN WHITENING CONTAINING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/085208    International Application No.:    PCT/KR2015/012571
Publication Date: 02.06.2016 International Filing Date: 23.11.2015
IPC:
C07K 5/00 (2006.01), C07K 7/06 (2006.01), A61K 8/64 (2006.01), A61Q 19/02 (2006.01), G01N 33/53 (2006.01)
Applicants: KNU-INDUSTRY COOPERATION FOUNDATION [KR/KR]; 1, Gangwondaehak-gil Chuncheon-si Gangwon-do 24341 (KR).
SUPADELIXIR INC. [KR/KR]; Medical School Building 1-410 1, Gangwondaehak-gil Chuncheon-si Gangwon-do 24341 (KR)
Inventors: HAHN, Jang-Hee; (KR).
LIM, Dong-Young; (KR)
Agent: OH, Kook-Jin; (KR)
Priority Data:
10-2014-0164481 24.11.2014 KR
Title (EN) SFRP5-DERIVED PEPTIDE FRAGMENT AND COSMETIC COMPOSITION FOR SKIN WHITENING CONTAINING SAME
(FR) FRAGMENT PEPTIDIQUE DÉRIVÉ DE SFRP5 ET COMPOSITION COSMÉTIQUE POUR LE BLANCHIMENT DE LA PEAU LE CONTENANT
(KO) SFRP5 유래의 펩타이드 단편 및 이를 포함하는 피부 미백용 화장료 조성물
Abstract: front page image
(EN)The present invention provides: a peptide fragment derived from secreted frizzled protein 5 (Sfrp5), that is, a peptide fragment selected from the group consisting of peptides composed of amino acid sequences of SEQ ID NOs: 1 to 9; and a cosmetic composition, containing the same as an active ingredient, for skin whitening and/or skin pigmentation suppression. The peptide fragment has an activity to suppress skin pigmentation by inhibiting melanogenesis in melanin cells. In addition, the present invention provides reagents for research or analysis, containing the peptide fragment to suppress Wnt signaling.
(FR)La présente invention concerne : un fragment peptidique dérivé de la Sfrp5 (secreted frizzled-related protein 5), c'est-à-dire un fragment peptidique choisi dans le groupe constitué de peptides composés des séquences d'acides aminés SEQ ID NO : 1 à 9 ; et une composition cosmétique le contenant en tant qu'ingrédient actif pour le blanchiment de la peau et/ou la suppression de la pigmentation de la peau. Le fragment peptidique présente une activité pour supprimer la pigmentation de la peau par inhibition de la mélanogénèse dans les cellules de mélanine. En outre, la présente invention concerne des réactifs pour la recherche ou l'analyse, contenant le fragment peptidique pour supprimer la voie de signalisation des protéines Wnt.
(KO)본 발명은 Sfrp5(Secreted frizzled protein 5)에서 유래한 펩타이드 단편, 즉 서열번호 1 내지 9의 아미노산 서열로 구성된 펩타이드로 이루어진 군으로부터 선택된 펩타이드 단편 및 이를 유효성분으로 포함하는 피부 미백용 및/또는 피부 색소 침착 억제용 화장료 조성물을 제공한다. 상기 펩타이드 단편은 멜라닌세포에서 멜라닌의 생성을 억제함으로써 피부색소의 침착을 억제하는 활성을 갖는다. 또한, 본 발명은 상기 펩타이드 단편을 포함하는 Wnt 신호전달 억제를 위한 연구 또는 분석용 시약을 제공한다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)