Processing

Please wait...

Settings

Settings

1. WO2016081384 - COMBINATION THERAPY COMPRISING OX40 BINDING AGONISTS AND PD-1 AXIS BINDING ANTAGONISTS

Publication Number WO/2016/081384
Publication Date 26.05.2016
International Application No. PCT/US2015/060941
International Filing Date 16.11.2015
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
337
having four-membered rings, e.g. taxol
C07K 16/28 (2006.01)
A61K 31/337 (2006.01)
CPC
A61K 2039/507
A61K 2039/55
A61K 38/16
A61K 39/3955
A61K 39/39558
A61K 45/06
Applicants
  • GENENTECH, INC. [US/US]; 1 DNA Way South San Francisco, CA 94080-4990, US (AE, AG, AM, AO, AU, AZ, BB, BF, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CI, CL, CM, CO, CR, CU, DM, DO, DZ, EC, EG, GA, GD, GE, GH, GM, GN, GQ, GT, GW, HN, ID, IL, IR, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LY, MA, MD, ME, MG, ML, MN, MR, MW, MX, MY, MZ, NA, NE, NG, NI, NZ, OM, PA, PE, PG, PH, QA, RU, RW, SA, SC, SD, SG, SL, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW)
  • F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel, CH (AL, AT, BA, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
Inventors
  • CHEUNG, Jeanne; US
  • HUSENI, Mahrukh; US
  • KIM, Jeong; US
Agents
  • ZHOU, Jie; US
Priority Data
62/080,99117.11.2014US
62/093,40017.12.2014US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMBINATION THERAPY COMPRISING OX40 BINDING AGONISTS AND PD-1 AXIS BINDING ANTAGONISTS
(FR) POLYTHÉRAPIE COMPRENANT DES AGONISTES SE LIANT À OX40 ET DES ANTAGONISTES SE LIANT À L'AXE PD-1
Abstract
(EN)
The invention provides compositions and methods for treating cancers. The comprises administering a PD-1 axis binding antagonist and an OX40 binding agonist
(FR)
L'invention concerne des compositions et des méthodes pour traiter des cancers. Une méthode selon l'invention consiste à administrer un antagoniste se liant à l'axe PD-1 et un agoniste se liant à OX40.
Latest bibliographic data on file with the International Bureau