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1. (WO2016065115) MATRIX-ASSISTED SPECTROPHOTOMETRY

Pub. No.:    WO/2016/065115    International Application No.:    PCT/US2015/056858
Publication Date: Fri Apr 29 01:59:59 CEST 2016 International Filing Date: Fri Oct 23 01:59:59 CEST 2015
IPC: B01L 3/00
B05D 3/10
G01N 27/28
G01N 33/487
Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Inventors: COLLINS, James J.
PARDEE, Keith
Title: MATRIX-ASSISTED SPECTROPHOTOMETRY
Abstract:
Disclosed herein are multiwell plates suitable for spectrophotometry for low-volume liquid samples. For the multiwell plates, the bottom of at least one well has a layer of porous matrix disposed thereon, or is comprised of a layer of porous matrix. The layer of porous matrix permits a low-volume liquid sample to distribute evenly across the porous matrix. Also disclosed herein are methods of performing a photometric or spectrophotometric measurement on a liquid sample having a small volume, by using a multiwell plate comprising a layer of porous matrix.