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1. (WO2016064202) THERMOSENSITIVE PLURONIC-CHITOSAN OLIGOSACCHARIDE-KARTOGENIN NANOCOMPOSITE WITH DUAL DRUG RELEASE FUNCTION

Pub. No.:    WO/2016/064202    International Application No.:    PCT/KR2015/011169
Publication Date: Fri Apr 29 01:59:59 CEST 2016 International Filing Date: Thu Oct 22 01:59:59 CEST 2015
IPC: A61K 9/16
A61K 47/36
A61K 31/196
A61P 19/02
Applicants: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
동국대학교 산학협력단
Inventors: IM, Gun Il
임군일
KANG, Mi Lan
강미란
Title: THERMOSENSITIVE PLURONIC-CHITOSAN OLIGOSACCHARIDE-KARTOGENIN NANOCOMPOSITE WITH DUAL DRUG RELEASE FUNCTION
Abstract:
The present invention relates to a thermosensitive dual drug carrier using pluronic-chitosan oligosaccharide-kartogenin nanocomposite. Since the drug carrier of the present invention has an ongoing cartilage regeneration effect and a rapid anti-cancer effect by controlling the release rate of analgesic drug encapsulated in a composite particle with karogenin, the drug carrier is expected to be capable of preventing or treating bone diseases more effectively.