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1. (WO2016064202) THERMOSENSITIVE PLURONIC-CHITOSAN OLIGOSACCHARIDE-KARTOGENIN NANOCOMPOSITE WITH DUAL DRUG RELEASE FUNCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/064202    International Application No.:    PCT/KR2015/011169
Publication Date: 28.04.2016 International Filing Date: 21.10.2015
IPC:
A61K 9/16 (2006.01), A61K 47/36 (2006.01), A61K 31/196 (2006.01), A61P 19/02 (2006.01)
Applicants: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR/KR]; 30, Pildong-ro 1-gil, Jung-gu, Seoul 04620 (KR)
Inventors: IM, Gun Il; (KR).
KANG, Mi Lan; (KR)
Agent: LEE, Myoung-Jin; (KR)
Priority Data:
10-2014-0143414 22.10.2014 KR
Title (EN) THERMOSENSITIVE PLURONIC-CHITOSAN OLIGOSACCHARIDE-KARTOGENIN NANOCOMPOSITE WITH DUAL DRUG RELEASE FUNCTION
(FR) NANOCOMPOSITE THERMOSENSIBLE À BASE DE PLURONIQUE - OLIGOSACCHARIDE DE CHITOSANE - KARTOGENIN, PRÉSENTANT UNE FONCTION DE RELARGAGE MÉDICAMENTEUX DOUBLE
(KO) 이중 약물 방출 기능을 가진 온도감응성 플루로닉-키토산올리고당-카토제닌 나노 복합체
Abstract: front page image
(EN)The present invention relates to a thermosensitive dual drug carrier using pluronic-chitosan oligosaccharide-kartogenin nanocomposite. Since the drug carrier of the present invention has an ongoing cartilage regeneration effect and a rapid anti-cancer effect by controlling the release rate of analgesic drug encapsulated in a composite particle with karogenin, the drug carrier is expected to be capable of preventing or treating bone diseases more effectively.
(FR)La présente invention concerne un support médicamenteux thermosensible à double médicament utilisant un nanocomposite à base de pluronique - oligosaccharide de chitosane - kartogenin. Le support médicamenteux de la présente invention présentant un effet de long terme de régénération du cartilage et un effet anticancéreux rapide grâce au contrôle de la vitesse de libération de médicament analgésique encapsulé dans une particule composite à base de kartogenin, il est attendu que le support médicamenteux soit apte à prévenir ou à traiter des maladies osseuses de façon plus efficace.
(KO)본 발명은 플루로닉-키토산올리고당-카토제닌 나노 복합체를 이용한 온도감응성 이중 약물 전달체에 관한 것이다. 본 발명의 약물 전달체는 카토제닌과 복합체 입자에 봉입된 진통제 약물의 방출 속도를 조절함으로써, 지속적인 연골 재생 효과 및 빠른 항염 효과를 가지는바, 골 질환의 예방 또는 치료에 있어서, 보다 효과적으로 접근하여 치료할 수 있을 것으로 기대된다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)