WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016063969) HEMAGGLUTININ-BINDING PEPTIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/063969    International Application No.:    PCT/JP2015/079931
Publication Date: 28.04.2016 International Filing Date: 23.10.2015
IPC:
C07K 7/08 (2006.01), A61K 38/00 (2006.01), A61P 31/16 (2006.01), C07K 7/64 (2006.01)
Applicants: PEPTIDREAM INC. [JP/JP]; 4-6-1, Komaba, Meguro-ku, Tokyo 1538505 (JP).
TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE [JP/JP]; 1-6, Kamikitazawa 2-chome, Setagaya-ku, Tokyo 1568506 (JP)
Inventors: KUBOTA, Kiichi; (JP).
REID, Patrick; (JP).
KOHARA, Michinori; (JP).
MASUYA, Keiichi; (JP).
OHUCHI, Masaki; (JP)
Agent: INABA, Yoshiyuki; (JP)
Priority Data:
2014-217582 24.10.2014 JP
Title (EN) HEMAGGLUTININ-BINDING PEPTIDE
(FR) PEPTIDE DE LIAISON À L'HÉMAGGLUTININE
(JA) ヘマグルチニン結合ペプチド
Abstract: front page image
(EN)The present invention address the problem of providing a hemagglutinin-binding peptide from which can be obtained an anti influenza virus effect that is stronger than that of preexisting peptides. Provided is a hemagglutinin-binding peptide, or the like, containing a polypeptide that comprises any of amino acid sequences (i) to (iv). (i) Thr-MeGly-Asp-MePhe-MePhe-Ser-MeSer-His-Tyr-Thr-Val-Pro-Arg (SEQ ID NO. 1). (ii) Arg-Val-Ser-MePhe-Thr-Tyr-MePhe-MeSer-Tyr-Thr-Pro-Ser (SEQ ID NO. 2). (iii) An amino acid sequence obtained by deleting, adding, or substituting one or more amino acids in SEQ ID NO. 1 or 2. (iv) An amino acid sequence having at least 90% sequence identity with SEQ ID NO. 1 or 2.
(FR)L'invention concerne un peptide se liant à l'hémagglutinine, permettant d'obtenir un effet contre le virus de la grippe supérieur à l'effet des peptides existants. Le peptide selon l'invention, ou analogue, contient un polypeptide comprenant une des séquences d'acides aminés i) à iv) suivantes : (i) Thr-MeGly-Asp-MePhe-MePhe-Ser-MeSer-His-Tyr-Thr-Val-Pro-Arg (SEQ ID NO 1) ; (ii) Arg-Val-Ser-MePhe-Thr-Tyr-MePhe-MeSer-Tyr-Thr-Pro-Ser (SEQ ID NO 2) ; (iii) une séquence d'acides aminés obtenue par délétion, addition ou substitution d'au moins un acide aminé dans SEQ ID NO 1 ou 2 ; (iv) une séquence d'acides aminés présentant au moins 90% d'identité de séquence avec SEQ ID NO 1 ou 2.
(JA) 本発明は、既存のペプチドのよりも高い抗インフルエンザウイルス効果が得られるヘマグルチニン結合ペプチドを提供することを課題とする。本発明は、以下の(i)から(iv)のいずれかのアミノ酸配列からなるポリペプチドを含むヘマグルチニン結合ペプチド等を提供する: (i) Thr-MeGly-Asp-MePhe-MePhe-Ser-MeSer-His-Tyr-Thr-Val-Pro-Arg(配列番号:1); (ii) Arg-Val-Ser-MePhe-Thr-Tyr-MePhe-MeSer-Tyr-Thr-Pro-Ser(配列番号:2); (iii) 配列番号:1又は2において、1又は数個のアミノ酸が欠失、付加又は置換されているアミノ酸配列;及び (iv) 配列番号:1又は2と90%以上配列同一性を有するアミノ酸配列。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)