Search International and National Patent Collections

1. (WO2016063299) A NOVEL PURIFICATION PROCESS FOR ISOLATION AND COMMERCIAL PRODUCTION OF RECOMBINANT TNK-TPA (TENECTEPLASE)

Pub. No.:    WO/2016/063299    International Application No.:    PCT/IN2015/050137
Publication Date: Fri Apr 29 01:59:59 CEST 2016 International Filing Date: Tue Oct 20 01:59:59 CEST 2015
IPC: C12N 1/14
Applicants: GENNOVA BIOPHARMACEUTICALS LIMITED
Inventors: RAGHUWANSHI, Arjun
SINGH KUMAR, Shrawan
KUMAR, Ankit
SAHOO RANJAN, Mihir
SINGH, Sanjay
Title: A NOVEL PURIFICATION PROCESS FOR ISOLATION AND COMMERCIAL PRODUCTION OF RECOMBINANT TNK-TPA (TENECTEPLASE)
Abstract:
The present invention relates to a novel process of isolating and purifying tissue plasminogen activator and its variants more specifically TNK-tPA from CHO cells and describes an industrially applicable, simple, cost effective, robust and highly efficient process of TNK-tPA purification.