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1. (WO2016062854) CONJUGATED MOLECULES COMPRISING A PEPTIDE DERIVED FROM THE CD4 RECEPTOR COUPLED TO AN ANIONIC POLYPEPTIDE FOR THE TREATMENT OF AIDS

Pub. No.:    WO/2016/062854    International Application No.:    PCT/EP2015/074598
Publication Date: Fri Apr 29 01:59:59 CEST 2016 International Filing Date: Sat Oct 24 01:59:59 CEST 2015
IPC: A61K 47/48
A61K 38/17
C07K 14/73
A61P 31/18
Applicants: INSTITUT PASTEUR
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
UNIVERSITE PARIS-SUD
UNIVERSITE GRENOBLE ALPES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Inventors: BALEUX, Françoise
LORTAT-JACOB, Hugues
BONNAFFE, David
COÏC, Yves-Marie
Title: CONJUGATED MOLECULES COMPRISING A PEPTIDE DERIVED FROM THE CD4 RECEPTOR COUPLED TO AN ANIONIC POLYPEPTIDE FOR THE TREATMENT OF AIDS
Abstract:
This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Said organic molecule comprises a 5 to 21 amino acid anionic polypeptide. Such a conjugated molecule can be used in antiviral treatment, namely in the treatment of AIDS.