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1. (WO2016062827) TOLEROGENIC DENDRITIC CELLS, METHODS OF PRODUCING THE SAME, AND USES THEREOF

Pub. No.:    WO/2016/062827    International Application No.:    PCT/EP2015/074536
Publication Date: Fri Apr 29 01:59:59 CEST 2016 International Filing Date: Fri Oct 23 01:59:59 CEST 2015
IPC: A61K 35/15
C12N 5/0784
A61K 35/12
Applicants: SOTIO A.S.
Inventors: PALOVÁ JELÍNKOVÁ, Lenka
DÁŇOVÁ, Klára
ŠPÍŠEK, Radek
Title: TOLEROGENIC DENDRITIC CELLS, METHODS OF PRODUCING THE SAME, AND USES THEREOF
Abstract:
Described herein are methods for the preparation of stable semi-mature tolerogenic dendritic cells and compositions comprising such stable semi-mature tolerogenic dendritic cells. The stable semi-mature tolerogenic dendritic cells described herein and compositions thereof can be used for the establishment of immune tolerance when treating an autoimmune disease, graft rejection and/or graft-versus-host disease.