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1. (WO2016061531) USE OF METHYLNALTREXONE TO ATTENUATE TUMOR PROGRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/061531    International Application No.:    PCT/US2015/056060
Publication Date: 21.04.2016 International Filing Date: 16.10.2015
IPC:
A01N 43/42 (2006.01)
Applicants: SALIX PHARMACEUTICALS, INC. [US/US]; 400 Somerset Corporate Boulevard Bridgewater, NJ 08807 (US).
UNIVERSITY OF CHICAGO [US/US]; (US)
Inventors: MOSS, Jonathan; (US).
JOHNSON, Lorin, K.; (US)
Agent: SPARKS, Jonathan, M.; (US)
Priority Data:
62/065,550 17.10.2014 US
62/140,876 31.03.2015 US
62/222,746 23.09.2015 US
Title (EN) USE OF METHYLNALTREXONE TO ATTENUATE TUMOR PROGRESSION
(FR) UTILISATION DE MÉTHYLNALTREXONE POUR ATTÉNUER UNE PROGRESSION DE TUMEUR
Abstract: front page image
(EN)Presented herein are methods for preventing or treating tumor growth, tumor metastasis and/or abnormal proliferation of tumor cells in a subject, wherein the methods involve administration of a pharmaceutical composition comprising methylnaltrexone. Also presented herein are methods for inhibiting or slowing the growth of a tumor in a subject, wherein the methods include selecting a subject who is a suitable candidate for treatment with methylnaltrexone, and administering a composition comprising methylnaltrexone to the subject.
(FR)L'invention concerne des procédés pour prévenir ou traiter une croissance tumorale, une métastase tumorale et/ou une prolifération anormale de cellules tumorales chez un sujet, les procédés impliquant l'administration d'une composition pharmaceutique comprenant de la méthylnaltrexone. L'invention concerne également des procédés pour inhiber ou ralentir la croissance d'une tumeur chez un sujet, les procédés consistant à sélectionner un sujet qui est un candidat approprié pour un traitement à base de méthylnaltrexone, et à administrer une composition comprenant de la méthylnaltrexone au sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)