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1. (WO2016061386) RNA APTAMERS AGAINST TRANSFERRIN RECEPTOR (TFR)

Pub. No.:    WO/2016/061386    International Application No.:    PCT/US2015/055792
Publication Date: Fri Apr 22 01:59:59 CEST 2016 International Filing Date: Fri Oct 16 01:59:59 CEST 2015
IPC: A61K 48/00
C07H 21/02
Applicants: CITY OF HOPE
APTERNA LTD
Inventors: ROSSI, John, J.
YOON, Sorah
HABIB, Nagy
Title: RNA APTAMERS AGAINST TRANSFERRIN RECEPTOR (TFR)
Abstract:
Provided herein, inter alia, are nucleic acid compounds capable of binding transferrin receptor on a cell and internalizing into said cell. The compositions provided herein may be useful for delivering therapeutic and diagnostic agents to a cell. Further provided are pharmaceutical compositions and methods of treatment using nucleic acid compounds provided herein.