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1. (WO2016061197) INSECTICIDAL POLYPEPTIDES HAVING IMPROVED ACTIVITY SPECTRUM AND USES THEREOF

Pub. No.:    WO/2016/061197    International Application No.:    PCT/US2015/055491
Publication Date: Fri Apr 22 01:59:59 CEST 2016 International Filing Date: Thu Oct 15 01:59:59 CEST 2015
IPC: C07K 14/325
C12N 15/32
Applicants: PIONEER HI-BRED INTERNATIONAL, INC.
Inventors: IZUMI WILCOXON, Michi
YAMAMOTO, Takashi
Title: INSECTICIDAL POLYPEPTIDES HAVING IMPROVED ACTIVITY SPECTRUM AND USES THEREOF
Abstract:
The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.