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1. (WO2016061160) DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/061160 International Application No.: PCT/US2015/055420
Publication Date: 21.04.2016 International Filing Date: 14.10.2015
IPC:
C07D 471/04 (2006.01) ,A61K 31/437 (2006.01) ,A61P 3/00 (2006.01) ,A61P 29/00 (2006.01) ,A61P 37/02 (2006.01)
Applicants: VITAE PHARMACEUTICALS, INC.[US/US]; 400 Interpace Parkway Parsippany, New Jersey 07054, US
Inventors: CLAREMON, David, A.; US
DILLARD, Lawrence, Wayne; US
DONG, Chengguo; US
FAN, Yi; US
JIA, Lanqi; US
LOTESTA, Stephen, D.; US
MARCUS, Andrew; US
SINGH, Suresh, B.; US
TICE, Colin, M.; US
YUAN, Jing; US
ZHAO, Wei; US
ZHENG, Yajun; US
ZHUANG, Linghang; US
Agent: DAVIS, Steven, G.; US
Priority Data:
62/063,91214.10.2014US
62/074,40603.11.2014US
Title (EN) DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA
(FR) INHIBITEURS DE ROR-GAMMA À BASE DE DIHYDROPYRROLOPYRIDINE
Abstract: front page image
(EN) Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
(FR) L'invention concerne de nouveaux composés de formule (I) : des sels pharmaceutiquement acceptables de ceux-ci, et des compositions pharmaceutiques de ceux-ci, qui sont utiles dans le traitement de maladies et de troubles à médiation par RORγ. L'invention concerne également des compositions pharmaceutiques comprenant les nouveaux composés de formule (I) et des procédés pour leur utilisation dans le traitement d'un ou de plusieurs troubles ou maladies inflammatoires, métaboliques, auto-immun(e)s et autres.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)