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1. (WO2016060096) PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND AND PHOSPHORYLCHOLINE COMPLEX
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/060096 International Application No.: PCT/JP2015/078862
Publication Date: 21.04.2016 International Filing Date: 13.10.2015
IPC:
C07F 9/09 (2006.01) ,C07F 9/572 (2006.01) ,C07K 14/47 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9
Compounds containing elements of the 5th Group of the Periodic System
02
Phosphorus compounds
06
without P-C bonds
08
Esters of oxyacids of phosphorus
09
Esters of phosphoric acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9
Compounds containing elements of the 5th Group of the Periodic System
02
Phosphorus compounds
547
Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
553
having one nitrogen atom as the only ring hetero atom
572
Five-membered rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
Applicants: NOF CORPORATION[JP/JP]; 20-3, Ebisu 4-chome, Shibuya-ku, Tokyo 1506019, JP
Inventors: SASAKI, Takashi; JP
FUJITA, Takanori; JP
IWAKIRI Norio; JP
YAMAMOTO, Nobuyuki; JP
Agent: OMORI, Junichi; JP
Priority Data:
2014-21054615.10.2014JP
2014-21054715.10.2014JP
Title (EN) PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND AND PHOSPHORYLCHOLINE COMPLEX
(FR) COMPOSÉ CONTENANT UN GROUPE PHOSPHORYLCHOLINE ET COMPLEXE DE PHOSPHORYLCHOLINE
(JA) ホスホリルコリン基含有化合物およびホスホリルコリン複合体
Abstract:
(EN) [Problem] To provide: a phosphorylcholine group-containing compound which is easily manufactured and with which a phosphorylcholine complex suitable for use as a phosphorylcholine antigen can be produced; and the phosphorylcholine complex. [Solution] The present invention is: a phosphorylcholine group-containing compound having a structure represented by formula (1); and a phosphorylcholine-protein complex having a structure in which the phosphorylcholine group-containing compound and an amino acid amine site of a protein are amide bonded. (X is a hydrogen atom or a monovalent cation residue, or a hydroxysuccinimide group.)
(FR) L'invention vise à procurer : un composé contenant un groupe phosphorylcholine qui est facilement fabriqué et grâce auquel un complexe de phosphorylcholine approprié pour être utilisé comme antigène de phosphorylcholine peut être produit ; et le complexe de phosphorylcholine. La présente invention concerne : un composé contenant un groupe phosphorylcholine ayant une structure représentée par la formule (1) ; et un complexe de phosphorylcholine-protéine ayant une structure dans laquelle le composé contenant un groupe phosphorylcholine et un site amine d'acide aminé d'une protéine sont liés par une liaison amide. (X est un atome d'hydrogène ou un résidu cation monovalent, ou un groupe hydroxysuccinimide.)
(JA) 【課題】製造が容易であり、かつホスホリルコリン抗原としての利用に適したホスホリルコリン複合体を生成可能なホスホリルコリン基含有化合物およびホスホリルコリン複合体を提供すること。 【解決手段】下記の式(1)で表される構造を有するホスホリルコリン基含有化合物、および該ホスホリルコリン基含有化合物と、蛋白質のアミノ酸アミン部位とがアミド結合した構造を有するホスホリルコリン-蛋白複合体。(Xは水素原子または1価のカチオン残基、もしくはヒドロキシスクシンイミド基である。)
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)