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1. (WO2016059650) 10-SUBSTITUTED COLCHICINOIDS AS POTENT ANTICANCER AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/059650    International Application No.:    PCT/IN2015/050135
Publication Date: 21.04.2016 International Filing Date: 14.10.2015
IPC:
C07C 233/41 (2006.01)
Applicants: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH [IN/IN]; Anusandhan Bhawan, Rafi Marg, New Delhi 110001 (IN)
Inventors: VISHWAKARMA, Ram; (IN).
BHARATE, Sandip Bibishan; (IN).
KUMAR, Ajay; (IN).
SINGH, Baljinder; (IN).
KUMAR, Ashok; (IN).
BHUSHAN, Shashi; (IN).
HAMID, Abid; (IN).
JOSHI, Prashant; (IN).
GURU, Santosh Kumar; (IN).
KUMAR, Suresh; (IN).
HUSSAIN, Aashiq; (IN).
QAZI, Asif Khurshid; (IN).
BHARATE, Sonali Sandip; (IN).
SHARMA, Parduman; (IN).
SAXENA, Ajit Kumar; (IN).
MONDHE, Dilip Manikrao; (IN).
MAHAJAN, Girish; (IN).
WANI, Zahoor; (IN)
Agent: KOUL, SUNAINA; RCY House, C-235, Defence Colony, New Delhi-110024, (IN)
Priority Data:
2929/DEL/2014 14.10.2014 IN
Title (EN) 10-SUBSTITUTED COLCHICINOIDS AS POTENT ANTICANCER AGENTS
(FR) COLCHICINOÏDES SUBSTITUÉS EN POSITION 10, UTILISÉS COMME AGENTS ANTICANCÉREUX PUISSANTS
Abstract: front page image
(EN)The present invention relates to the compounds of formula I wherein R is as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10-substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease.
(FR)La présente invention concerne les composés de formule I, dans laquelle R est tel que décrit dans la description. La présente invention concerne en particulier la synthèse et l'activité antiproliférative de colchicinoïdes substitués en position 10. Les composés de l'invention peuvent être utilisés pour la prévention ou dans le traitement d'une maladie cancéreuse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)