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1. (WO2016059635) ANALYTE-SENSING DEVICE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/059635 International Application No.: PCT/IL2015/051022
Publication Date: 21.04.2016 International Filing Date: 13.10.2015
IPC:
A61B 5/00 (2006.01) ,A61B 5/145 (2006.01) ,A61B 5/1459 (2006.01) ,A61B 5/1455 (2006.01) ,G01N 21/64 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1455
using optical sensors, e.g. spectral photometrical oximeters
1459
invasive, e.g. introduced into the body by a catheter
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1455
using optical sensors, e.g. spectral photometrical oximeters
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
64
Fluorescence; Phosphorescence
Applicants: GLUSENSE LTD.[IL/IL]; 3 Pekeris Street Rabin Science Park 76702 Rehovot, IL
Inventors: BRILL, Boaz; IL
Agent: COLB, Sanford T.; Sanford T. Colb & CO. P.O. Box 2273 76122 Rehovot, IL
Priority Data:
62/063,21113.10.2014US
Title (EN) ANALYTE-SENSING DEVICE
(FR) DISPOSITIF DE DÉTECTION D'ANALYTE
Abstract:
(EN) An implantable unit (30) includes fluorescent sensor molecules (40), each of which comprises a binding site for an analyte, and at least one fluorescent moiety configured to emit fluorescent light; and an implantable-unit light source (42) configured to generate light having an illumination peak wavelength appropriate for excitation of the fluorescent moiety. An external system (26) includes an external reading unit (32), which comprises a light sensor (44), which is configured to sense fluorescent light emitted from the fluorescent moiety having an emission peak wavelength, wherein the emission peak wavelength is between 100 and 500 nm greater than the illumination peak wavelength; and one or more processors (60), which are configured to: drive the implantable-unit light source (42) to generate the light; receive, from the light sensor (44), at least one measurement of the fluorescent light emitted from the fluorescent moiety; and calculate the concentration of the analyte in a subject based on the at least one measurement.
(FR) Une unité implantable (30) comprend des molécules de détection fluorescentes (40) comprenant chacune un site de liaison pour un analyte, et au moins une fraction fluorescente configurée pour émettre une lumière fluorescente; et une unité source de lumière implantable (42) configurée pour générer une lumière dont la longueur d'onde de crête d'éclairage est adaptée pour exciter la fraction fluorescente. Un système externe (26) comprend une unité de lecture externe (32) comprenant un capteur de lumière (44) configuré pour détecter la lumière fluorescente émise à partir de la fraction fluorescente. La longueur d'onde de crête d'émission de la fraction fluorescente est de 100 à 500 nm supérieure à la longueur d'onde de crête d'éclairage. Le système externe comprend également un ou plusieurs processeurs (60) configurés pour : commander à l'unité source de lumière implantable (42) de générer la lumière; recevoir, du capteur de lumière (44), au moins un mesurage de la lumière fluorescente émise à partir de la fraction fluorescente; et calculer la concentration d'analyte dans un sujet, d'après le ou les mesurages.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)