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1. (WO2016059436) METHOD FOR NANOPORE RNA CHARACTERISATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/059436    International Application No.:    PCT/GB2015/053097
Publication Date: 21.04.2016 International Filing Date: 19.10.2015
IPC:
C12Q 1/68 (2006.01)
Applicants: OXFORD NANOPORE TECHNOLOGIES LIMITED [GB/GB]; Edmund Cartwright House 4 Robert Robinson Avenue Oxford Science Park Oxford OX4 4GA (GB)
Inventors: GARALDE, Daniel Ryan; (GB).
HERON, Andrew John; (GB).
JAYASINGHE, Lakmal; (GB).
TURNER, Daniel John; (GB).
WHITE, James; (GB)
Agent: CHAPMAN, Lee Phillip; (GB)
Priority Data:
1418459.2 17.10.2014 GB
1508270.4 14.05.2015 GB
1517634.0 06.10.2015 GB
PCT/GB2015/052916 06.10.2015 GB
Title (EN) METHOD FOR NANOPORE RNA CHARACTERISATION
(FR) PROCÉDÉ DE CARACTÉRISATION D'ARN À NANOPORES
Abstract: front page image
(EN)The invention relates to a new method of characterising a target RNA polynucleotide by taking one or more measurements as the target RNA polynucleotide moves with respect to a transmembrane pore. The movement is controlled by a DNA helicase. The invention also relates to a modified RNA construct wherein the RNApolynucleotidehas been modified to increase DNA helicase binding thereto.
(FR)L'invention concerne un nouveau procédé de caractérisation d'un polynucléotide d'ARN cible par prise d'une ou de plusieurs mesures tandis que ledit polynucléotide d'ARN cible se déplace par rapport à un pore transmembranaire. Le déplacement est commandé par une hélicase d'ADN. L'invention concerne également une construction d'ARN modifiée, le polynucléotide d'ARN ayant été modifié afin d'augmenter la liaison de l'hélicase d'ADN à celui-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)