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1. (WO2016058704) CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES

Pub. No.:    WO/2016/058704    International Application No.:    PCT/EP2015/002054
Publication Date: Fri Apr 22 01:59:59 CEST 2016 International Filing Date: Sat Oct 17 01:59:59 CEST 2015
IPC: A61K 51/04
A61P 19/00
Applicants: SCV GMBH
Inventors: RÖSCH, Frank
MECKEL, Marian
Title: CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES
Abstract:
The invention relates to a compound V for complexing metallic isotopes, comprising a chelator X and one or more targeting vectors conjugated with the chelator X, said targeting vectors having the structure -L1-R1-L2-R2-L3-R3, wherein R3 contains a bisphosphonate. A pharmaceutical consists of the compound V and a metallic isotope which is complexed with compound V.