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1. (WO2016058704) CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/058704    International Application No.:    PCT/EP2015/002054
Publication Date: 21.04.2016 International Filing Date: 16.10.2015
IPC:
A61K 51/04 (2006.01), A61P 19/00 (2006.01)
Applicants: SCV GMBH [DE/DE]; Kurt-Schumacher-Str. 22 55270 Zornheim (DE)
Inventors: RÖSCH, Frank; (DE).
MECKEL, Marian; (DE)
Agent: GRAF VON STOSCH, Andreas; Graf von Stosch Patentanwaltsgesellschaft mbH Prinzregentenstr. 22 80538 München (DE)
Priority Data:
10 2014 115 154.2 17.10.2014 DE
Title (DE) KONJUGIERTE BISPHOSPHONATE FÜR DIE DIAGNOSTIK UND THERAPIE VON KNOCHENERKRANKUNGEN
(EN) CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES
(FR) BISPHOSPHONATE CONJUGUÉ POUR LE DIAGNOSTIC ET LE TRAITEMENT DE MALADIES OSSEUSES
Abstract: front page image
(DE)Die Erfindung betrifft eine Verbindung V zum Komplexieren von metallischen Isotopen, umfassend einen Chelator X und einen oder mehrere, mit dem Chelator X konjugierte, Targetingvektoren mit der Struktur -L1-R1-L2-R2-L3-R3, wobei R3 ein Bisphosphonat enthält. Ein Pharmakon besteht aus der Verbindung V und einem mit der Verbindung V komplexierten metallischen Isotop.
(EN)The invention relates to a compound V for complexing metallic isotopes, comprising a chelator X and one or more targeting vectors conjugated with the chelator X, said targeting vectors having the structure -L1-R1-L2-R2-L3-R3, wherein R3 contains a bisphosphonate. A pharmaceutical consists of the compound V and a metallic isotope which is complexed with compound V.
(FR)L'invention concerne un composé V destiné à complexer des isotopes métalliques, comprenant un chélateur X et un ou plusieurs vecteurs de ciblage conjugués avec le chélateur, présentant la structure -L1-R1-L2-R2-L3-R3, R3 contenant un bisphosphonate. Un médicament comprend le composé V et un isotope métallique complexé avec le composé V.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)