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1. WO2016058056 - NOVEL IMAGING COMPOSITION AND USES THEREOF

Publication Number WO/2016/058056
Publication Date 21.04.2016
International Application No. PCT/AU2015/050640
International Filing Date 16.10.2015
IPC
C07C 235/80 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
235Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
70having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
72with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
80having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
C07C 247/14 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
247Compounds containing azido groups
14with azido groups bound to carbon atoms of rings other than six-membered aromatic rings
C07C 261/02 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
261Derivatives of cyanic acid
02Cyanates
C07K 17/06 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
17Carrier-bound or immobilised peptides; Preparation thereof
02Peptides being immobilised on, or in, an organic carrier
06attached to the carrier via a bridging agent
A61K 51/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
02characterised by the carrier
04Organic compounds
08Peptides, e.g. proteins
10Antibodies or immunoglobulins; Fragments thereof
A61K 103/20 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
103Radioactive metals
20Indium
CPC
A61K 31/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
18Sulfonamides
A61K 51/1051
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
02characterised by the carrier ; , i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
04Organic compounds
08Peptides, e.g. proteins ; , carriers being peptides, polyamino acids, proteins
10Antibodies or immunoglobulins; Fragments thereof ; , the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
1045against animal or human tumor cells or tumor cell determinants
1051the tumor cell being from breast, e.g. the antibody being herceptin
C07C 259/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
259Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
04without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
06having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
C07C 2601/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
2601Systems containing only non-condensed rings
04with a four-membered ring
C07C 309/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
309Sulfonic acids; Halides, esters, or anhydrides thereof
01Sulfonic acids
02having sulfo groups bound to acyclic carbon atoms
03of an acyclic saturated carbon skeleton
13containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
14containing amino groups bound to the carbon skeleton
C07C 311/19
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
311Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
16having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
19to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
Applicants
  • THE UNIVERSITY OF MELBOURNE [AU]/[AU]
Inventors
  • DONNELLY, Paul Stephen
  • RUDD, Stacey Erin
  • WILLIAMS, Spencer John
Agents
  • FPA PATENT ATTORNEYS PTY LTD
Priority Data
201490413816.10.2014AU
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL IMAGING COMPOSITION AND USES THEREOF
(FR) NOUVELLE COMPOSITION D'IMAGERIE ET SES UTILISATIONS
Abstract
(EN) The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging agents when bound to an appropriate metal centre, particularly for the imaging of tumours.
(FR) La présente invention concerne des composés à base d'acides hydroxamiques, qui sont utiles comme agents d'imagerie lorsqu'ils sont liés à un centre métallique approprié, notamment pour effectuer une imagerie de tumeurs.
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