WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016057932) THERAPEUTIC INHIBITION OF LACTATE DEHYDROGENASE AND AGENTS THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/057932 International Application No.: PCT/US2015/054959
Publication Date: 14.04.2016 International Filing Date: 09.10.2015
IPC:
C12N 15/113 (2010.01) ,A61K 31/7088 (2006.01) ,A61P 7/00 (2006.01) ,A61P 13/12 (2006.01) ,A61P 35/00 (2006.01)
Applicants: DICERNA PHARMACEUTICALS, INC.[US/US]; 87 Cambridgepark Drive Cambridge, MA 02140, US
Inventors: BROWN, Bob, D.; US
DUDEK, Henryk, T.; US
LAI, Cheng; US
Agent: COWLES, Christopher, R.; US
Priority Data:
62/062,42410.10.2014US
62/199,05630.07.2015US
Title (EN) THERAPEUTIC INHIBITION OF LACTATE DEHYDROGENASE AND AGENTS THEREFOR
(FR) INHIBITION THÉRAPEUTIQUE DE LA LACTATE-DÉSHYDROGÉNASE ET AGENTS ASSOCIÉS
Abstract: front page image
(EN) This invention relates to compounds, compositions, and methods useful for reducing lactate dehydrogenase target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.
(FR) La présente invention concerne des composés, des compositions et des méthodes utilisés pour réduire les taux de protéines et d'ARN cibles de la lactate déshydrogénase au moyen de l'utilisation d'ARN bicaténaires, par exemple, d'agents de type ARNsi de substrat pour Dicer (ARNsiD).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)