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1. (WO2016057834) HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES

Pub. No.:    WO/2016/057834    International Application No.:    PCT/US2015/054761
Publication Date: Fri Apr 15 01:59:59 CEST 2016 International Filing Date: Fri Oct 09 01:59:59 CEST 2015
IPC: A61K 31/506
A61K 31/5377
C07D 413/14
Applicants: BIOMARIN PHARMACEUTICAL INC.
Inventors: BHAGWAT, Shripad
WANG, Bing
LUEDTKE, Gregory R.
SPYVEE, Mark
Title: HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES
Abstract:
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions in need of inhibition of heparan sulfate biosynthesis.