WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016057795) IMPROVED PEPTIDE INHIBITORS OF SODIUM CHANNELS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/057795 International Application No.: PCT/US2015/054693
Publication Date: 14.04.2016 International Filing Date: 08.10.2015
IPC:
A61K 38/04 (2006.01) ,A61K 38/16 (2006.01) ,A61P 1/00 (2006.01) ,A61P 11/06 (2006.01) ,A61P 11/08 (2006.01) ,A61P 11/12 (2006.01) ,C07K 14/435 (2006.01)
Applicants: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL[US/US]; 100 Europa Drive Suite 430 Chapel Hill, North Carolina 27517, US
SPYRYX BIOSCIENCES, INC.[US/US]; 15 TW Alexander Drive Research Triangle Park, North Carolina 27709, US
Inventors: TARRAN, Robert; US
CHRISTENSEN, Dale J.; US
Agent: MYERS BIGEL SIBLEY & SAJOVEC, PA; P.O. Box 37428 Raleigh, North Carolina 27627, US
Priority Data:
62/061,46108.10.2014US
Title (EN) IMPROVED PEPTIDE INHIBITORS OF SODIUM CHANNELS
(FR) INHIBITEURS PEPTIDIQUES AMÉLIORÉS DE CANAUX SODIQUES
Abstract: front page image
(EN) The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
(FR) La présente invention concerne la capacité de peptides spécialisés d'origine non naturelle à se lier aux canaux sodiques et à inhiber l'activation des canaux sodiques. L'invention concerne, en outre, des méthodes de régulation de l'absorption du sodium et du volume de fluide, ainsi que de traitement de troubles sensibles à la modulation de l'absorption du sodium par modulation de la liaison de peptides spécialisés d'origine non naturelle aux canaux sodiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)