WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016057762) SUBSTITUTED PYRIMIDINES AS INHIBITORS OF HIF PROLYL HYDROXYLASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/057762    International Application No.:    PCT/US2015/054643
Publication Date: 14.04.2016 International Filing Date: 08.10.2015
IPC:
C07D 239/26 (2006.01)
Applicants: MERCK SHARP & DOHME CORP [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US).
UJJAINWALLA, Fez [US/US]; (US) (US only).
TAN, John Qiang [US/US]; (US) (US only).
DANG, Qun [US/US]; (US) (US only).
SINZ, Christopher J. [US/US]; (US) (US only).
CRESPO, Alejandro [AR/US]; (US) (US only).
WANG, Ming [US/US]; (US) (US only).
CHEN, Yili [US/US]; (US) (US only).
CAI, Jiaqiang [GB/CN]; (CN) (US only).
WU, Fan [CN/CN]; (CN) (US only).
DU, Xiaoxing [CN/CN]; (CN) (US only)
Inventors: UJJAINWALLA, Fez; (US).
TAN, John Qiang; (US).
DANG, Qun; (US).
SINZ, Christopher J.; (US).
CRESPO, Alejandro; (US).
WANG, Ming; (US).
CHEN, Yili; (US).
CAI, Jiaqiang; (CN).
WU, Fan; (CN).
DU, Xiaoxing; (CN)
Common
Representative:
MERCK SHARP & DOHME CORP; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US)
Priority Data:
PCT/CN2014/088318 10.10.2014 CN
Title (EN) SUBSTITUTED PYRIMIDINES AS INHIBITORS OF HIF PROLYL HYDROXYLASE
(FR) PYRIMIDINES SUBSTITUÉES EN TANT QU'INHIBITEURS DE HIF PROLYL HYDROXYLASE
Abstract: front page image
(EN)The present invention concerns compounds of Formula I that inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
(FR)La présente invention concerne des composés de formule I qui inhibent la HIF prolyl hydroxylase, leur utilisation pour améliorer la production endogène d'érythropoïétine, et pour traiter des états associés à une production endogène réduite d'érythropoïétine, tels que l'anémie et des états analogues, ainsi que des compositions pharmaceutiques contenant un tel composé et un excipient pharmaceutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)