Search International and National Patent Collections
|1. (WO2016057730) CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR|
|Applicants:||VERTEX PHARMACEUTICALS INCORPORATED
CAESAR, JR., John P.
CONNELLY, Patrick Raymond
MCCLAIN, Brian R.
NTI-ADDAE, Kwame Wiredu
|Title:||CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR|
The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and a co-former and methods for their preparation. The present disclosure further relates to pharmaceutical compositions comprising the co-crystal forms, as well as methods of treatment therewith and kits.