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1. (WO2016057705) BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO CHIMERIC ANTIGEN RECEPTOR THERAPY AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/057705 International Application No.: PCT/US2015/054542
Publication Date: 14.04.2016 International Filing Date: 07.10.2015
IPC:
G01N 33/574 (2006.01) ,C12N 5/0783 (2010.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
078
Cells from blood or from the immune system
0783
T cells; NK cells; Progenitors of T or NK cells
Applicants: BEDOYA, Felipe[CO/US]; US (US)
BITTER, Hans[US/US]; US (US)
BROGDON, Jennifer[US/US]; US (US)
DORFMEIER, Corin[US/US]; US (US)
GARG, Abhishnek; US (US)
GLASS, David[US/US]; US (US)
MANNICK, Joan[US/US]; US (US)
MELENHORST, Jan, J.[US/US]; US (US)
MILONE, Michael, C.[US/US]; US (US)
MURPHY, Leon[US/US]; US (US)
ORLANDO, Elena[US/US]; US (US)
WILCOX, Nicholas[US/US]; US (US)
NOVARTIS AG[CH/CH]; Lichtstrasse 35 CH-4056 Basel, CH
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA[US/US]; 3160 Chestnut Street, Suite 200 Philadelphia, PA 19104, US
Inventors: BEDOYA, Felipe; US
BITTER, Hans; US
BROGDON, Jennifer; US
DORFMEIER, Corin; US
GARG, Abhishnek; US
GLASS, David; US
MANNICK, Joan; US
MELENHORST, Jan, J.; US
MILONE, Michael, C.; US
MURPHY, Leon; US
ORLANDO, Elena; US
WILCOX, Nicholas; US
Agent: KOYFMAN, Hannah, R.; US
Priority Data:
62/061,55308.10.2014US
62/144,68208.04.2015US
Title (EN) BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO CHIMERIC ANTIGEN RECEPTOR THERAPY AND USES THEREOF
(FR) BIOMARQUEURS PRÉDICTIFS DE LA RÉACTIVITÉ THÉRAPEUTIQUE À UNE THÉRAPIE PAR RÉCEPTEURS ANTIGÉNIQUES CHIMÈRES ET LEURS UTILISATIONS
Abstract:
(EN) Cancer biomarkers and methods of using them are disclosed.
(FR) Des biomarqueurs du cancer et des méthodes d'utilisation de ceux-ci sont divulgués.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)