Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
6. (WO2016057572) MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/057572 International Application No.: PCT/US2015/054316
Publication Date: 14.04.2016 International Filing Date: 06.10.2015
IPC:
A01N 41/06 (2006.01) ,A61K 31/18 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
41
Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
02
containing a sulfur-to-oxygen double bond
04
Sulfonic acids; Derivatives thereof
06
Sulfonic acid amides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
18
Sulfonamides
Applicants:
VERTEX PHARMACEUTICALS INCORPORATED [US/US]; 50 Northern Avenue Boston, Massachusetts 02210, US
Inventors:
MILLER, Mark Thomas; US
ANDERSON, Corey; US
ARUMUGAM, Vijayalaksmi; US
BEAR, Brian Richard; US
BINCH, Hayley Marie; US
CLEMENS, Jeremy J.; US
CLEVELAND, Thomas; US
CONROY, Erica; US
COON, Timothy Richard; US
FRIEMAN, Bryan A.; US
GROOTENHUIS, Peter Diederik Jan; US
GROSS, Raymond Stanley; US
HADIDA-RUAH, Sara Sabina; US
KHATUYA, Haripada; US
JOSHI, Pramod Virupax; US
KRENITSKY, Paul John; US
LIN, Chun-Chieh; US
MARELIUS, Gulin Erdogan; US
MELILLO, Vito; US
MCCARTNEY, Jason; US
NICHOLLS, Georgia McGaughey; US
PIERRE, Fabrice Jean Denis; US
SILINA, Alina; US
TERMIN, Andreas P.; US
UY, Johnny; US
ZHOU, Jinglan; US
Agent:
LI, Wen; US
Priority Data:
62/060,18206.10.2014US
62/114,76711.02.2015US
62/153,12027.04.2015US
Title (EN) MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
(FR) MODULATEURS DU RÉGULATEUR DE CONDUCTANCE TRANSMEMBRANAIRE DE LA MUCOVISCIDOSE
Abstract:
(EN) The present invention features a compound of formula (I): (I) or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.
(FR) La présente invention concerne un composé de formule (I): (I) ou un sel pharmaceutiquement acceptable de celui-ci, où R1, R2, R3, W, X, Y, Z, n, o, p et q sont tels que définis dans la description, lequel composé est utile pour le traitement de maladies médiées par le CFTR, telles que la mucoviscidose. La présente invention concerne également des compositions pharmaceutiques, une méthode de traitement et des kits correspondants.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)