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Machine translation
1. (WO2016057370) SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/057370 International Application No.: PCT/US2015/053941
Publication Date: 14.04.2016 International Filing Date: 05.10.2015
IPC:
C07D 473/40 (2006.01)
Applicants: SIGNAL PHARMACEUTICALS, LLC[US/US]; 10300 Campus Point Drive, Suite 100 San Diego, CA 92121, US
Inventors: ALEXANDER, Matthew; US
BAHMANYAR, Sogole; US
BOYLAN, John, Fredrerick; US
HANSEN, Joshua; US
HUANG, Dehua; US
HUBBARD, Robert; US
JEFFY, Brandon; US
LEISTEN, Jim; US
MOGHADDAM, Mehran; US
RAHEJA, Raj, K.; US
RAYMON, Heather; US
SCHWARZ, Kimberly; US
SLOSS, Marianne; US
TORRES, Eduardo; US
TRAN, Tam, Minh; US
XU, Shuichan; US
ZHAO, Jingjing; US
Agent: BRUNER, Michael, J.; US
Priority Data:
62/060,33906.10.2014US
Title (EN) SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
(FR) COMPOSÉS AMINOPURINE SUBSTITUÉS, COMPOSITIONS CORRESPONDANTES, ET PROCÉDÉS DE TRAITEMENT LES UTILISANT
Abstract: front page image
(EN) Provided herein are Aminopurine Compounds having the following structures wherein R1, R2, and R3 are as defined herein, composition comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma. Provided herein are compounds having the following formula (I) and pharmaceutically acceptable salts, tautomers, isotopologues, and stereoisomers thereof, wherein R1, R2 and R3 are as defined herein.
(FR) La présente invention concerne des composés aminopurine ayant les structures suivantes, R1, R2, et R3 étant tels que définis dans la description, la composition comprenant une quantité efficace d'un composé aminopurine, et des procédés de traitement ou de prévention d'un cancer, par exemple, d'un mélanome. La présente invention décrit des composés ayant la formule suivante (I) et leurs sels, tautomères, isotopologues, et stéréo-isomères pharmaceutiquement acceptables, R1, R2 et R3 étant tels que définis dans la description.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)