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1. (WO2016056653) CARDIOMYOCYTE PRODUCTION METHOD, VENTRICULAR CARDIOMYOCYTES AND PRODUCTION METHOD THEREFOR, AND SCREENING METHOD

Pub. No.:    WO/2016/056653    International Application No.:    PCT/JP2015/078784
Publication Date: Fri Apr 15 01:59:59 CEST 2016 International Filing Date: Sat Oct 10 01:59:59 CEST 2015
IPC: C12N 5/077
C12N 5/10
C12N 15/09
C12Q 1/06
Applicants: THE UNIVERSITY OF TOKYO
国立大学法人東京大学
Inventors: NAITO Atsuhiko
内藤 篤彦
KOMURO Issei
小室 一成
Title: CARDIOMYOCYTE PRODUCTION METHOD, VENTRICULAR CARDIOMYOCYTES AND PRODUCTION METHOD THEREFOR, AND SCREENING METHOD
Abstract:
Provided are: a cardiomyocyte production method with which it is possible to produce high-quality cardiomyocytes; ventricular cardiomyocytes having high quality, reduced cardiomyocyte heterogeneity, and reduced contamination with non-cardiomyocytes, and a production method for said ventricular cardiomyocytes; and a method using cardiomyocytes and/or ventricular cardiomyocytes for screening preventive or therapeutic drugs that treat at least one of hypertrophic cardiomyopathy, cardiomegaly, and Noonan syndrome.