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1. (WO2016055836) METHOD FOR PRODUCING AND USING THE RK39-KDDR PROTEIN AND LEISHMANIASIS DIAGNOSTIC KIT

Pub. No.:    WO/2016/055836    International Application No.:    PCT/IB2014/065188
Publication Date: Fri Apr 15 01:59:59 CEST 2016 International Filing Date: Fri Oct 10 01:59:59 CEST 2014
IPC: C07K 14/44
A61K 39/008
C12N 15/30
G01N 33/569
A61P 33/02
Applicants: UNIVERSIDADE FEDERAL DE MINAS GERAIS - UFMG
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MINAS GERAIS- FAPEMIG
Inventors: FUJIWARA, Ricardo Toshio
BARTHOLOMEU, Daniella Castanheira
BUENO, Lilian Lacerda
LEMOS, Lucas De Carvalho Dhom
CUNHA, João Luis Reis
MENDES, Tiago António De Oliveira
Title: METHOD FOR PRODUCING AND USING THE RK39-KDDR PROTEIN AND LEISHMANIASIS DIAGNOSTIC KIT
Abstract:
The present technology relates to a new heterologous expression process for the kinesin repeat, using specific primers which make it possible to construct a recombinant antigen with 7.5 repeats of K39 associated with a degenerated repeat, the KDDR (Kinesin Degenerated Derived Repeat). Also described is the use of this antigen (K39-KDDR) to diagnose leishmaniasis and as a vaccine, and a diagnostic kit containing this antigen.