Search International and National Patent Collections

1. (WO2016055496) BACE1 INHIBITORS

Pub. No.:    WO/2016/055496    International Application No.:    PCT/EP2015/073077
Publication Date: Fri Apr 15 01:59:59 CEST 2016 International Filing Date: Thu Oct 08 01:59:59 CEST 2015
IPC: C07D 513/04
A61K 31/554
A61K 31/542
A61P 25/28
Applicants: F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.
Inventors: BARTELS, Bjoern
CUENI, Philipp
DOLENTE, Cosimo
GUBA, Wolfgang
HAAP, Wolfgang
KUGLSTATTER, Andreas
OBST SANDER, Ulrike
PETERS, Jens-Uwe
ROGERS-EVANS, Mark
VIFIAN, Walter
WOLTERING, Thomas
Title: BACE1 INHIBITORS
Abstract:
The present invention provides a compound of formula I, having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.