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|1. (WO2016055169) AUTOMATIC METHOD FOR MONITORING CELL CULTURE GROWTH|
|Applicants:||FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
MATHIS, Harald Peter
|Title:||AUTOMATIC METHOD FOR MONITORING CELL CULTURE GROWTH|
The invention relates to an automated method for monitoring cell culture growth, in particular bacterial growth, wherein a receiving dish (24) is provided with a nutrient medium (38), on and/or in which a cell culture is applied, in particular a sample of human or animal tissue, such as blood, to which bacteria has been added, and which also contains one or a number of reagents, in particular antibiotics. A microscope (10) having a camera (18) and an image-capturing plane that can move along the optical axis (20) is provided, and the receiving dish (24) is brought into the microscope (10) in the nutrient medium (38), in order to monitor a potential growth of the cell culture. An image of the nutrient medium (38) is captured using the camera (18) of the microscope (10), at pre-determinable time intervals in the in particular single-digit minute region.