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1. (WO2016054998) METHOD FOR INHIBITING SURVIVAL, TUMORIGENESIS AND METASTASIS OF CANCER CELLS AND/OR CANCER STEM CELLS

Pub. No.:    WO/2016/054998    International Application No.:    PCT/CN2015/091452
Publication Date: Fri Apr 15 01:59:59 CEST 2016 International Filing Date: Fri Oct 09 01:59:59 CEST 2015
IPC: A61K 38/02
A61K 39/395
A61K 31/00
A61P 35/00
Applicants: HUNG, Shih-Chieh
Inventors: HUNG, Shih-Chieh
HSU, Han-Shui
Title: METHOD FOR INHIBITING SURVIVAL, TUMORIGENESIS AND METASTASIS OF CANCER CELLS AND/OR CANCER STEM CELLS
Abstract:
The present invention provides a new method for inhibiting and preventing survival, tumorigenesis and metastasis of cancer stem cells (CSCs) in a subject using Collagen XVII (Col XVII) inhibitor to CSCs, or a use of Col XVII inhibitor for the manufacture of a medicament for inhibiting and preventing survival, tumorigenesis and metastasis of CSCs. The present invention also provides a pharmaceutical composition for inhibiting and preventing survival, tumorigenesis and metastasis of cancer stem cells, comprising an effective amount of Col XVII inhibitor.