WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016054486) HYDROGEN PEROXIDE-ACTIVATED COMPOUNDS AS SELECTIVE ANTI-CANCER THERAPEUTICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/054486    International Application No.:    PCT/US2015/053687
Publication Date: 07.04.2016 International Filing Date: 02.10.2015
IPC:
A61K 31/167 (2006.01)
Applicants: UNIVERSITY OF CINCINNATI [US/US]; 51 Goodman Drive Suite 240 Cincinnati, Ohio 45221 (US)
Inventors: MERINO, Edward J.; (US).
MULLOY, James; (US).
VADUKOOT, Anish K.; (US).
WUNDERLICH, Mark; (US).
ABDULSALAM, Safnas F.; (US)
Agent: LIVINGSTON, Jennifer L.; (US)
Priority Data:
62/058,706 02.10.2014 US
Title (EN) HYDROGEN PEROXIDE-ACTIVATED COMPOUNDS AS SELECTIVE ANTI-CANCER THERAPEUTICS
(FR) COMPOSÉS ACTIVÉS PAR DU PEROXYDE D'HYDROGÈNE SERVANT D'AGENTS THÉRAPEUTIQUES ANTI-CANCÉREUX SÉLECTIFS
Abstract: front page image
(EN)Provided are compounds according to the following Formula I: The Formula I compounds are activated in the presence of hydrogen peroxide and are therefore selective anti-cancer therapeutics for cancers associated with elevated reactive oxygen species (ROS). Also provided are methods and pharmaceutical compositions for treating cancers associated with increased ROS.
(FR)La présente invention concerne des composés de formule suivante I : Les composés de formule I sont activés en présence de peroxyde d'hydrogène et constituent par conséquent des agents thérapeutiques anti-cancéreux sélectifs pour des cancers associés à un niveau élevé d'espèces réactives de l'oxygène (ROS). L'invention concerne également des procédés et des compositions pharmaceutiques pour le traitement de cancers associés à une augmentation des ROS.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)