WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016054452) ECOTIN VARIANTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/054452    International Application No.:    PCT/US2015/053610
Publication Date: 07.04.2016 International Filing Date: 01.10.2015
IPC:
C07H 21/04 (2006.01)
Applicants: ANSUN BIOPHARMA, INC. [US/US]; 3030 Callan Road San Diego, California 92121 (US)
Inventors: FANG, fang; (US)
Agent: MEIKLEJOHN, Anita L., Ph.D.; (US)
Priority Data:
62/058,639 01.10.2014 US
Title (EN) ECOTIN VARIANTS
(FR) VARIANTS D'ÉCOTINE
Abstract: front page image
(EN)Ecotin variants and their use in treating viral hemorrhagic fever are described. Described herein are methods for treating systemic inflammatory response syndrome or viral hemorrahagic fever by administering an ecotin polypeptide. Described herein is a polypeptide comprising the amino acid sequence of any of SEQ ID NOs: 2-9 and 11-18. Also described: is a polypeptide comprising the amino acid sequence of any of SEQ ID NO: 11-18 preceded by a methionine; a polypeptide comprising the amino acid sequence of any of SEQ ID NO: 11 -18 with up to 5 single amino acid changes or deletions provided that the polypeptide does not comprise the amino acid sequence of SEQ ID NO: 10.
(FR)La présente invention concerne des variants d'écotine et leur utilisation dans le traitement de la fièvre hémorragique virale. L'invention porte sur des méthodes de traitement du syndrome de réponse inflammatoire systémique ou de fièvre hémorragique virale par administration d'un polypeptide d'écotine; sur un polypeptide comprenant la séquence d'acides aminés telle qu'une séquence parmi les SEQ ID NOs: 2-9 et 11-18; sur un polypeptide comprenant la séquence d'acides aminés telle qu'une séquence parmi les SEQ ID NOs: 11-18 avec 5 changements ou délétions d'acides aminés uniques à condition que le polypeptide ne comprenne pas la séquence d'acides aminés de la SEQ ID NO: 10.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)