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1. (WO2016054295) SYSTEMS AND METHODS FOR DETERMINING PROBATIVE SAMPLES AND ISOLATION AND QUANTITATION OF CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/054295    International Application No.:    PCT/US2015/053370
Publication Date: 07.04.2016 International Filing Date: 30.09.2015
IPC:
C12M 1/34 (2006.01), C12M 3/00 (2006.01), C12Q 1/68 (2006.01)
Applicants: DXNOW INC. [US/US]; 5 Jennison Circle Natick, Massachusetts 01760 (US).
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. [US/US]; 75 Francis Street Boston, Massachusetts 02115 (US).
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY [US/US]; Office of the General Counsel Building 170, 3rd Floor, Main Quad P.O. Box 20386 Stanford, California 94305-2038 (US).
KLEVAN, Leonard [US/US]; (US).
DEMIRCI, Utkan [US/US]; (US).
INCI, Fatih [TR/US]; (US)
Inventors: KLEVAN, Leonard; (US).
DEMIRCI, Utkan; (US).
INCI, Fatih; (US)
Agent: HOPKINS, Brian P.; (US)
Priority Data:
62/058,072 30.09.2014 US
Title (EN) SYSTEMS AND METHODS FOR DETERMINING PROBATIVE SAMPLES AND ISOLATION AND QUANTITATION OF CELLS
(FR) SYSTÈMES ET PROCÉDÉS DE DÉTERMINATION D'ÉCHANTILLONS PROBANTS ET D'ISOLEMENT ET DE QUANTIFICATION DE CELLULES
Abstract: front page image
(EN)Embodiments of the present disclosure relate to a platform for at least one of capturing, identifying and studying biological materials, and more particularly, to microfluidic channel platforms (for example) for detecting and/or identifying samples containing sperm cells, and isolating and analyzing captured sperm cells for DNA analysis (for example). In some embodiments, such microfluidic platforms integrate imaging technology. Such embodiments provide the ability to at least one of rapidly isolate and quantitate sperm cells from biological mixtures as occur in sexual assault evidence, for example, thereby enhancing identification of suspects in these cases and contributing to the safety of society.
(FR)La présente invention concerne, dans des modes de réalisation, une plate-forme permettant de capturer et/ou d'identifier et/ou d'étudier des matériels biologiques et, plus particulièrement, des plates-formes à canaux microfluidiques (par exemple) permettant de détecter et/ou d'identifier des échantillons contenant des spermatozoïdes, et d'isoler et d'analyser les spermatozoïdes capturés pour une analyse d'ADN (par exemple). Dans certains modes de réalisation, ces plates-formes microfluidiques intègrent une technologie d'imagerie. Ces modes de réalisation permettent d'isoler rapidement et/ou quantifier des spermatozoïdes à partir de mélanges biologiques, comme dans le cas d'une collecte de preuves lors d'une agression sexuelle par exemple, ce qui améliore ainsi l'identification des suspects dans ces situations et contribue à la sécurité de la société.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)