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1. (WO2016053771) INHIBITORS OF IRAK4 ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/053771 International Application No.: PCT/US2015/052111
Publication Date: 07.04.2016 International Filing Date: 25.09.2015
IPC:
A61K 31/444 (2006.01) ,A61K 31/506 (2006.01) ,A61K 45/06 (2006.01)
Applicants: ALTMAN, Michael, D.[US/US]; US (NZ, US)
ANDRESEN, Brian, M.[US/US]; US (NZ, US)
BRUBAKER, Jason, D.[US/US]; US (NZ, US)
CHILDERS, Matthew, L.[US/US]; US (NZ, US)
DONOFRIO, Anthony[US/US]; US (NZ, US)
FISCHMANN, Thierry[US/US]; US (US)
GIBEAU, Craig, R.[US/US]; US (NZ, US)
KATTAR, Solomon, D.[US/US]; US (NZ, US)
LESBURG, Charles, A.[US/US]; US (NZ, US)
LIM, Jongwon[US/US]; US (NZ, US)
MACLEAN, John, K. F.[GB/GB]; GB (NZ, US)
MANSOOR, Umar, F.[GB/US]; US (NZ, US)
NORTHRUP, Alan, B.[US/US]; US (NZ, US)
SANDERS, John, M.[US/US]; US (NZ, US)
SMITH, Graham, F.[GB/US]; US (NZ, US)
TORRES, Luis[US/US]; US (NZ, US)
MERCK SHARP & DOHME CORP.[US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW)
Inventors: ALTMAN, Michael, D.; US
ANDRESEN, Brian, M.; US
BRUBAKER, Jason, D.; US
CHILDERS, Matthew, L.; US
DONOFRIO, Anthony; US
FISCHMANN, Thierry; US
GIBEAU, Craig, R.; US
KATTAR, Solomon, D.; US
LESBURG, Charles, A.; US
LIM, Jongwon; US
MACLEAN, John, K. F.; GB
MANSOOR, Umar, F.; US
NORTHRUP, Alan, B.; US
SANDERS, John, M.; US
SMITH, Graham, F.; US
TORRES, Luis; US
Common
Representative:
MERCK SHARP & DOHME CORP.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US
Priority Data:
62/057,69230.09.2014US
Title (EN) INHIBITORS OF IRAK4 ACTIVITY
(FR) INHIBITEURS DE L'ACTIVITÉ DE IRAK 4
Abstract:
(EN) The present invention relates to inhibitors of IRAK4 of Formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.
(FR) La présente invention a trait à des inhibiteurs d'IRAK 4 de formule I. Cette invention concerne des compositions comprenant de tels inhibiteurs, ainsi que des méthodes utilisant celles-ci pour le traitement d'états pathologiques ou de maladies à médiation par IRAK 4 ou associés à IRAK 4.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)