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1. (WO2016053770) INHIBITORS OF IRAK4 ACTIVITY

Pub. No.:    WO/2016/053770    International Application No.:    PCT/US2015/052106
Publication Date: Fri Apr 08 01:59:59 CEST 2016 International Filing Date: Sat Sep 26 01:59:59 CEST 2015
IPC: A61K 31/444
A61K 31/506
A61K 45/06
Applicants: MERCK SHARP & DOHME CORP.
ALTMAN, Michael, D.
ANDRESEN, Brian, M.
BRUBAKER, Jason, D.
DONOFRIO, Anthony
FISCHMANN, Thierry
GIBEAU, Craig, R.
LESBURG, Charles, A.
LIM, Jongwon
MACLEAN, John, K. F.
MANSOOR, Umar, F.
NORTHRUP, Alan, B.
SANDERS, John, M.
SMITH, Graham, F.
TORRES, Luis
Inventors: ALTMAN, Michael, D.
ANDRESEN, Brian, M.
BRUBAKER, Jason, D.
DONOFRIO, Anthony
FISCHMANN, Thierry
GIBEAU, Craig, R.
LESBURG, Charles, A.
LIM, Jongwon
MACLEAN, John, K. F.
MANSOOR, Umar, F.
NORTHRUP, Alan, B.
SANDERS, John, M.
SMITH, Graham, F.
TORRES, Luis
Title: INHIBITORS OF IRAK4 ACTIVITY
Abstract:
The present invention relates to inhibitors of IRAK4 of Formula I and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.