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1. (WO2016053613) FLOW CELL MODULES AND LIQUID SAMPLE ANALYZERS AND METHODS INCLUDING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/053613    International Application No.:    PCT/US2015/050143
Publication Date: 07.04.2016 International Filing Date: 15.09.2015
IPC:
G01N 21/03 (2006.01), G01N 21/05 (2006.01), G01N 21/64 (2006.01), G01J 3/44 (2006.01)
Applicants: PERKINELMER HEALTH SCIENCES, INC. [US/US]; 940 Winter Street Waltham, Massachusetts 02451 (US)
Inventors: DICESARE, Joseph L.; (US).
JIN, Feng; (US).
NEAL, Timothy P.; (US).
AIKENS, David; (US)
Agent: BEATTY, David, D.; (US)
Priority Data:
14/501,544 30.09.2014 US
Title (EN) FLOW CELL MODULES AND LIQUID SAMPLE ANALYZERS AND METHODS INCLUDING SAME
(FR) MODULES DE CUVE DE CIRCULATION ET ANALYSEURS D'ÉCHANTILLON DE LIQUIDE, ET PROCÉDÉS LES INCLUANT
Abstract: front page image
(EN)A flow cell (250) for a fluorescence spectrometer includes a flow channel (254) to receive a flow of a liquid sample, an excitation light entrance window to receive excitation light from a light source, and an emission light exit window to transmit fluorescent emission light from the liquid sample in the flow channel from the flow cell. The excitation light entrance window and/or emission light exit window includes a waveguide including: a waveguide core (261, 262) formed of a core material; and a cladding medium (274) surrounding a portion of the waveguide core (261, 262), wherein the cladding medium (274) has a refractive index less than the refractive index of the core material. The waveguide defines a portion of the flow channel (254). At least one mirror (270, 272) integral with the flow cell body is positioned to reflect excitation light that has passed through the liquid sample in the flow channel (254) back into the liquid sample and/or to reflect emission light emitted from the liquid sample toward the emission light exit window. The excitation light entrance window is spaced a first distance from the flow channel and the emission light exit window is spaced a second distance from the flow channel, whereby the second distance is less than the first distance.
(FR)L'invention concerne une cuve de circulation pour un spectromètre de fluorescence comprenant un canal d'écoulement destiné à recevoir un écoulement d'un échantillon de liquide, une fenêtre d'entrée de lumière d'excitation destinée à recevoir une lumière d'excitation en provenance d'une source de lumière, et une fenêtre de sortie de lumière d'émission destinée à émettre la lumière d'émission fluorescente en provenance de l'échantillon de liquide dans le canal d'écoulement à partir de la cuve de circulation. La fenêtre d'entrée de lumière d'excitation et/ou la fenêtre de sortie de lumière d'émission comprennent un guide d'ondes comprenant : un cœur de guide d'ondes formé d'un matériau de cœur; et un support de gaine entourant une partie du cœur de guide d'ondes, le support de gaine présentant un indice de réfraction inférieur à l'indice de réfraction du matériau de cœur. Le guide d'ondes définit une partie du canal d'écoulement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)