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1. (WO2016053392) METHOD OF TREATING CANCER AND MYOCARDIAL INFARCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/053392 International Application No.: PCT/US2015/033723
Publication Date: 07.04.2016 International Filing Date: 02.06.2015
IPC:
A61K 31/506 (2006.01) ,A61K 31/497 (2006.01) ,A61K 31/675 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
506
not condensed and containing further heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
4965
Non-condensed pyrazines
497
containing further heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
66
Phosphorus compounds
675
having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
HSU, Ming Chu [US/US]; US
HUANG, Ying-Huey; TW
YEN, Chi-Feng; TW
KING, Chi-Hsin Richard [US/US]; US
TAIGEN BIOTECHNOLOGY CO. LTD.; 7F, 138 Shin Ming Road Neihu Dist. Taipei 11470, TW
Inventors:
HSU, Ming Chu; US
HUANG, Ying-Huey; TW
YEN, Chi-Feng; TW
KING, Chi-Hsin Richard; US
Agent:
TSAO, Y. Rocky; US
Priority Data:
14/502,14430.09.2014US
Title (EN) METHOD OF TREATING CANCER AND MYOCARDIAL INFARCTION
(FR) PROCÉDÉ DE TRAITEMENT DU CANCER ET DE L'INFARCTUS DU MYOCARDE
Abstract:
(EN) A method of sensitizing a cancer cell to a chemotherapy agent or tracking myocardial infarction. The method includes administering to a subject in need thereof an effective amount of a compound of formula (I), wherein R1 is C3-20 cycloalkyl, each R2 is H or C1-6 alkyl, L1 is C3-20 heterocycloalkyl, L2 is C3-20 cycloalkyl, and m, n, o, p, and q are each independently 0-6.
(FR) L'invention concerne un procédé de sensibilisation d'une cellule cancéreuse à un agent chimiothérapeutique ou de suivi d'un infarctus du myocarde. Le procédé consiste à administrer à un sujet le nécessitant une quantité efficace d'un composé de formule (I), dans lequel R1 représente un groupe cycloalkyle en C3-20, chaque R2 représente H ou un groupe alkyle en C1-6, L1 représente un groupe hétéroalkyle en C3-20, L2 représente un groupe cycloalkyle en C3-20, et m, n, o, p et q valent chacun indépendamment de 0 à 6.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)