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1. (WO2016052522) PREPARATION FOR PERCUTANEOUS ADMINISTRATION AND PACKAGE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/052522    International Application No.:    PCT/JP2015/077547
Publication Date: 07.04.2016 International Filing Date: 29.09.2015
IPC:
A61K 31/4045 (2006.01), A61K 9/70 (2006.01), A61K 47/10 (2006.01), A61K 47/22 (2006.01), A61K 47/32 (2006.01), A61P 25/16 (2006.01)
Applicants: NIPRO CORPORATION [JP/JP]; 3-9-3, Honjo-Nishi, Kita-ku, Osaka-shi, Osaka 5318510 (JP)
Inventors: KAWAMURA, Naohisa; (JP).
SHINKAI, Norihiro; (JP).
SHIRAISHI, Hiroaki; (JP).
TSUDA, Yo; (JP)
Agent: HAYASHI, Kazuyoshi; (JP)
Priority Data:
2014-201991 30.09.2014 JP
Title (EN) PREPARATION FOR PERCUTANEOUS ADMINISTRATION AND PACKAGE
(FR) PRÉPARATION POUR ADMINISTRATION PERCUTANÉE ET EMBALLAGE
(JA) 経皮投与製剤及び包装体
Abstract: front page image
(EN)The purpose of the present invention is to provide a method for preventing the degeneration of ropinirole in a ropinirole-containing preparation for percutaneous administration. A preparation for percutaneous administration, said preparation comprising a support and an adhesive layer disposed on the support, wherein the adhesive layer contains ropinirole or a pharmacologically acceptable salt thereof and mercaptobenzimidazole. The content of mercaptobenzimidazole may be 0.10-5.00 mass% relative to the adhesive layer.
(FR)La présente invention concerne un procédé pour prévenir la dégradation du ropinirole dans une préparation contenant du ropinirole pour administration percutanée. L’invention concerne une préparation pour administration percutanée, ladite préparation comprenant un support et une couche adhésive disposée sur le support, la couche adhésive contenant du ropinirole ou un sel pharmacologiquement acceptable de celui-ci et du mercaptobenzimidazole. La teneur en mercaptobenzimidazole peut être de 0,10 à 5,00 % en masse par rapport à la couche adhésive.
(JA) ロピニロール含有経皮投与製剤中のロピニロールの変性を防ぐ方法を提供すること。 本発明は、支持体と、前記支持体上に位置する粘着剤層と、を備える経皮投与製剤であって、前記粘着剤層は、ロピニロール又はその薬理学的に許容できる塩、及びメルカプトベンズイミダゾールを含む経皮投与製剤を提供する。前記メルカプトベンズイミダゾールの含量は、前記粘着剤層に対して0.10~5.00質量%であってもよい。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)