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1. (WO2016052282) NON-INVASIVE IN SITU GLUCOSE LEVEL SENSING USING ELECTROMAGNETIC RADIATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/052282 International Application No.: PCT/JP2015/076825
Publication Date: 07.04.2016 International Filing Date: 14.09.2015
IPC:
A61B 5/00 (2006.01) ,A61B 5/05 (2006.01) ,G01N 21/21 (2006.01) ,G01N 21/3581 (2014.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
05
Measuring for diagnosis by means of electric currents or magnetic fields
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
17
Systems in which incident light is modified in accordance with the properties of the material investigated
21
Polarisation-affecting properties
[IPC code unknown for G01N 21/3581]
Applicants:
ADVANTEST CORPORATION [JP/JP]; 32-1, Asahicho 1-chome, Nerima-ku, Tokyo 1790071, JP
Inventors:
SHANG, Yang; SG
Agent:
SAITO, Tatsuya; Inspire Patent and Trademark Attorneys, Akasaka Abitasion Building 6F, Akasaka 1-3-5, Minato-ku, Tokyo 1070052, JP
Priority Data:
14/80830324.07.2015US
14/80840924.07.2015US
62/05970203.10.2014US
Title (EN) NON-INVASIVE IN SITU GLUCOSE LEVEL SENSING USING ELECTROMAGNETIC RADIATION
(FR) DÉTECTION NON INVASIVE IN SITU DU TAUX DE GLUCOSE FAISANT APPEL À UN RAYONNEMENT ÉLECTROMAGNÉTIQUE
Abstract:
(EN) System and method of using electromagnetic radiation signals to non-invasively test a glucose level in a subject. During operation, an incident beam of Terahertz waves is generated and projected onto the surface of the eyeball, which is naturally reflected by a tear layer. The reflected Terahertz waves are detected and characterized to determine the reflection characteristics of the tear layer, e.g., an axial ratio of reflection coefficients in two polarization orientations. Provided with the determined axial ratio and according to a predetermined correlation among axial ratio, tear glucose level and blood glucose level, the current blood glucose level in the subject can be derived and presented to a user.
(FR) La présente invention concerne un système et une méthode d'utilisation de signaux de rayonnement électromagnétique pour évaluer de manière non invasive un taux de glucose chez un sujet. Pendant le fonctionnement, un faisceau incident d'ondes Térahertz est généré et projeté sur la surface du globe oculaire, qui est naturellement réfléchi par une couche de fluide lacrymal. Les ondes Térahertz réfléchies sont détectées et caractérisées pour déterminer les caractéristiques de réflexion de la couche de fluide lacrymal, par exemple, un rapport axial de coefficients de réflexion selon deux orientations de polarisation. En faisant appel au rapport axial déterminé et en fonction d'une corrélation prédéfinie entre le rapport axial, le taux de glucose dans le fluide lacrymal et le taux de glucose dans le sang, le taux actuel de glucose dans le sang chez le sujet peut être dérivé et présenté à un utilisateur.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)