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1. (WO2016051791) FUNGAL GLUCOSYLCERAMIDE AS A VACCINE FOR FUNGAL INFECTIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/051791 International Application No.: PCT/JP2015/004972
Publication Date: 07.04.2016 International Filing Date: 30.09.2015
IPC:
A61K 31/7028 (2006.01) ,A61K 31/10 (2006.01) ,A61K 36/06 (2006.01) ,A61K 39/00 (2006.01) ,A61K 39/39 (2006.01)
Applicants: KOHJIN LIFE SCIENCES CO., LTD.[JP/JP]; 1-3, Yurakucho 1-chome, Chiyoda-ku, Tokyo 1000006, JP
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK[US/US]; 35 State Street Albany, New York 12207, US
Inventors: DEL POETA, Maurizio; US
MOR, Visesato; US
SATO, Toshiya; JP
NAKAGAWA, Tomohiro; JP
Agent: ENOMOTO, Masahiko; JP
Priority Data:
62/058,62201.10.2014US
Title (EN) FUNGAL GLUCOSYLCERAMIDE AS A VACCINE FOR FUNGAL INFECTIONS
(FR) GLUCOSYLCÉRAMIDE FONGIQUE EN TANT QUE VACCIN CONTRE LES INFECTIONS FONGIQUES
(JA) 真菌感染症に対するグリコシルセラミドの利用
Abstract:
(EN) The present invention features compositions that include a fungal glucosylceramide (GlcCer) purified from a non-pathogenic fungus (e.g., Candida utilis) and, optionally, an adjuvant. The invention also features methods of treating a patient who has a fungal disease and methods of preventing a fungal disease in a subject by administration of these compositions. Also within the scope of the invention are methods of formulating a fungal vaccine by: (a) providing a fungal glucosylceramide isolated from a non-pathogenic fungus; and (b) combining the fungal glucosylceramide with an adjuvant in a physiologically acceptable excipient.
(FR) La présente invention concerne des compositions qui comprennent un glucosylcéramide fongique (GlcCer) purifié d'un champignon non pathogène (par exemple, Candida utilis) et, facultativement, un adjuvant. L'invention concerne également des procédés de traitement d'un patient qui a une maladie fongique et des procédés de prévention d'une maladie fongique chez un sujet par l'administration de ces compositions. La présente invention concerne en outre des procédés de formulation d'un vaccin fongique par : (a) la fourniture d'un glucosylcéramide fongique isolé d'un champignon non pathogène; et (b) la combinaison du glucosylcéramide avec un adjuvant dans un excipient physiologiquement acceptable.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)