Processing

Please wait...

Settings

Settings

Goto Application

1. WO2016051159 - MUCOADHESIVE CARRIERS OF PARTICLES, METHOD OF PREPARATION AND USES THEREOF

Publication Number WO/2016/051159
Publication Date 07.04.2016
International Application No. PCT/GB2015/052833
International Filing Date 29.09.2015
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 9/70 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
CPC
A61K 9/006
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0053Mouth and digestive tract, i.e. intraoral and peroral administration
006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
A61K 9/145
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
145with organic compounds
A61K 9/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
19lyophilised ; , i.e. freeze-dried, solutions or dispersions
A61K 9/7007
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7007Drug-containing films, membranes or sheets
Applicants
  • VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKARSTVÍ [CZ]/[CZ]
  • UNIVERZITA PALACKÉHO V OLOMOUCHI [CZ]/[CZ]
  • TECHNICKÁ UNIVERZITA V LIBERCI [CZ]/[CZ]
  • GLOBALACORN LTD. [GB]/[GB]
Inventors
  • MAŠEK, Josef
  • LUKÁC, Róbert
  • RAŠKA, Milan
  • KNÖTIGOVÁ, Pavlína Turánek
  • TURÁNEK, Jaroslav
  • LUBASOVÁ, Daniela
  • MILLER, Andrew David
Agents
  • WRIGHT, Simon M
Priority Data
PV 2014-66529.09.2014CZ
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MUCOADHESIVE CARRIERS OF PARTICLES, METHOD OF PREPARATION AND USES THEREOF
(FR) EXCIPIENTS MUCO-ADHÉSIFS DE PARTICULES, LEUR PROCÉDÉ DE PRÉPARATION ET D'UTILISATION
Abstract
(EN)
The present invention relates to a mucoadhesive carrier system, for particles,which comprises nanoscaffold having a nanofibrous layer with a thickness of from 0.1 to 1000 µm, carrying a substance in the form of particles. The mucoadhesive layer,in at least a part of its surface, overlaps the nanoscaffold. A process for its preparation and its use for delivery of the vaccines and therapeutics to mucosal surfaces is also disclosed.
(FR)
La présente invention concerne un système d'excipients muco-adhésifs, pour particules, qui comprend un nano-échafaudage pourvu d'une couche nanofibreuse ayant une épaisseur comprise entre 0,1 et 1000 µm, transportant une substance sous la forme de particules. La couche mucoadhésive, dans au moins une partie de sa surface, chevauche le nano-échafaudage. L'invention concerne également son procédé de préparation et son utilisation dans l'administration de vaccins et d'agents thérapeutiques aux surfaces des muqueuses.
Latest bibliographic data on file with the International Bureau