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1. (WO2016050867) ANTIBODIES TO TICAGRELOR AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/050867 International Application No.: PCT/EP2015/072606
Publication Date: 07.04.2016 International Filing Date: 30.09.2015
IPC:
C07K 16/44 (2006.01) ,C07D 487/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
44
against material not provided for elsewhere
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
MEDIMMUNE LIMITED [GB/GB]; Milstein Building Granta Park Cambridge Cambridgeshire CB21 6GH, GB
Inventors:
BUCHANAN, Andrew; GB
NYLANDER, Sven; SE
PENNEY, Mark; GB
NEWTON, Philip; GB
KEYES, Feenagh; GB
INGHARDT, Tord; SE
Agent:
WINTER, Christopher; GB
Priority Data:
62/058,45801.10.2014US
62/114,93111.02.2015US
Title (EN) ANTIBODIES TO TICAGRELOR AND METHODS OF USE
(FR) ANTICORPS À TICAGRELOR ET PROCÉDÉS DE LEUR UTILISATION
Abstract:
(EN) The disclosure generally provides antibodies and antigen binding fragments of antibodies that bind ticagrelor and metabolites of ticagrelor. The disclosure also provides compositions comprising the antibodies, nucleic acid molecules encoding the antibodies, methods of treating a patient comprising administering the antibodies, and methods of making and using the antibodies.
(FR) L'invention concerne des anticorps et des fragments de liaison à l'antigène d'anticorps qui se lient au ticagrelor et aux métabolites au ticagrelor. L'invention concerne également des compositions comprenant les anticorps, des molécules d'acides nucléiques codant les anticorps, des méthodes de traitement d'un patient comprenant l'administration des anticorps, et des procédés de fabrication et d'utilisation des anticorps.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)