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1. (WO2016027211) PROCESS FOR THE PREPARATION OF CINACALCET AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/027211 International Application No.: PCT/IB2015/056205
Publication Date: 25.02.2016 International Filing Date: 14.08.2015
IPC:
C07C 209/28 (2006.01) ,C07C 45/29 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
209
Preparation of compounds containing amino groups bound to a carbon skeleton
24
by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
28
by reduction with other reducing agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
45
Preparation of compounds having CO groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
27
by oxidation
29
of hydroxy groups
Applicants:
MEHTA API PVT. LTD. [IN/IN]; 203, Centre Point, 2nd Floor, Near Hotel Kohinoor, J.B. Nagar, Andheri-Kurla Road, Andheri (East), Maharashtra, Mumbai 400 059, IN
Inventors:
KHAN, Rao, Uwais, Ahmad; IN
PATHAK, Rajesh, Harshnath; IN
PATIL, Chetan, Vinesh; IN
GAIKWAD, Sanjay, Ramrao; IN
APAR, Shrikrishna, Motiram; IN
LINGE, Govind, Udhavrao; IN
SHAIKH, Mohammad, Umar; IN
Agent:
MAJUMDAR, Subhatosh; IN
GANGULI, Dr., Sanchita; IN
SEN, Abhishek; IN
VENKATESH, Mythili; IN
MAJUMDAR, Amrita; IN
KUNDU, Subarna; IN
CHAUBEY, Priyanka; IN
Priority Data:
2635/MUM/201418.08.2014IN
Title (EN) PROCESS FOR THE PREPARATION OF CINACALCET AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
(FR) PROCÉDÉ POUR LA PRÉPARATION DE CINACALCET ET DE SES SELS PHARMACEUTIQUEMENT ACCEPTABLES
Abstract:
(EN) The present invention relates to an efficient process for the preparation of Cinacalcet of formula (II) and its pharmaceutically acceptable salts thereof of formula (I), in particular Cinacalcet Hydrochloride of formula (Ia) in higher yields and purity.
(FR) La présente invention concerne un procédé efficace pour la préparation de cinacalcet de formule (II) et de ses sels pharmaceutiquement acceptables de formule (I), en particulier le chlorhydrate de cinacalcet de formule (Ia), avec des rendements et une pureté supérieurs.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)