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1. WO2016027204 - DEVICE FOR THE FRACTIONATION OF OBJECTS AND FRACTIONATION METHOD

Publication Number WO/2016/027204
Publication Date 25.02.2016
International Application No. PCT/IB2015/056195
International Filing Date 14.08.2015
IPC
G01N 30/00 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
CPC
B01L 2200/0605
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0605Metering of fluids
B01L 2200/0647
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0647Handling flowable solids, e.g. microscopic beads, cells, particles
B01L 2200/0652
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0647Handling flowable solids, e.g. microscopic beads, cells, particles
0652Sorting or classification of particles or molecules
B01L 2300/0867
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
0867Multiple inlets and one sample wells, e.g. mixing, dilution
B01L 2300/0887
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0887Laminated structure
B01L 2400/082
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
08Regulating or influencing the flow resistance
082Active control of flow resistance, e.g. flow controllers
Applicants
  • STEM SEL S.R.L. [IT]/[IT]
Inventors
  • DI VENERE, Martina
Agents
  • GRÜNECKER PATENT-UND RECHTSANWÄLTE PARTG MBB
Priority Data
VI2014A00021420.08.2014IT
Publication Language English (EN)
Filing Language Italian (IT)
Designated States
Title
(EN) DEVICE FOR THE FRACTIONATION OF OBJECTS AND FRACTIONATION METHOD
(FR) DISPOSITIF DE FRACTIONNEMENT D'OBJETS ET PROCÉDÉ DE FRACTIONNEMENT
Abstract
(EN)
The present invention relates to a device and a method for dynamic fractionation of a dispersed phase in a fluid. The device comprises a fractionation channel and from a first to a third injection ports. A first and a second confining fluids are injectable through the first and second injection ports, respectively. An elution fluid for transporting the dispersed phase is injectable into the channel through a third injection port which is arranged between the first and second injection ports. An end portion of the channel comprises from a first to a third terminal portion respectively arranged in correspondence to the first to the third injection ports and having a geometry such that the first and second confining fluids respectively have a first and second predefined flow rate and the elution fluid have a third predefined flow rate which is larger than the first and second predefined flow rates.
(FR)
La présente invention concerne un dispositif et un procédé de fractionnement dynamique d'une phase dispersée dans un fluide. Ledit dispositif comporte un canal de fractionnement allant d'un premier à un troisième orifice d'injection. Un premier et un deuxième fluide de confinement peuvent être injectés respectivement par les premier et deuxième orifices d'injection. Un fluide d'élution servant à transporter la phase dispersée peut être injecté dans le canal par un troisième orifice d'injection qui est disposé entre les premier et deuxième orifices d'injection. Une partie d'extrémité du canal comporte des première à troisième parties terminales respectivement disposées de façon à correspondre aux premier à troisième orifices d'injection et présentant une géométrie telle que les premier et deuxième fluides de confinement présentent respectivement un premier et un deuxième débit prédéfini et que le fluide d'élution présente un troisième débit prédéfini supérieur aux premier et deuxième débits prédéfinis.
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