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1. WO2016025762 - ANTI-METHANOGENIC COMPOSITIONS AND USES THEREOF

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Publication Number WO/2016/025762
Publication Date 18.02.2016
International Application No. PCT/US2015/045140
International Filing Date 13.08.2015
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61K 9/22 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
22Sustained or differential release type
CPC
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/22
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
A61K 31/351
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
351not condensed with another ring
A61K 31/366
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
365Lactones
366having six-membered rings, e.g. delta-lactones
A61K 47/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K 47/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
12Carboxylic acids; Salts or anhydrides thereof
Applicants
  • CEDARS-SINAI MEDICAL CENTER [US]/[US]
  • SYNTHETIC BIOLOGICS, INC. [US]/[US]
Inventors
  • PIMENTEL, Mark
  • MATHUR, Ruchi
  • KANZER, Steve
  • WACHER, Vince
Agents
  • LEVY, Seth D.
Priority Data
62/036,94813.08.2014US
62/043,64929.08.2014US
62/043,78929.08.2014US
62/141,35501.04.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-METHANOGENIC COMPOSITIONS AND USES THEREOF
(FR) COMPOSITIONS ANTI-MÉTHANOGÉNIQUES ET LEURS UTILISATIONS
front page image
Abstract
(EN)
The present invention relates to, in part, methods and compositions for the treatment of methanogen-associated disorders such as, for example, Irritable Bowel Syndrome (IBS). Particularly, modified-release formulations comprising at least one antimethanogenic statin are provided which release the antimethanogenic statin in the intestines.
(FR)
La présente invention concerne, en partie, des méthodes et des compositions pour le traitement de troubles d'ordre méthanogène tels que, par exemple, le syndrome du côlon irritable (SII). En particulier, l'invention concerne des formulations à libération modifiée comprenant au moins une statine antiméthanogène qui libèrent la statine antiméthanogène dans les intestins.
Also published as
AU2015301596
BR112017002761
CA2955666
CN106687107
EP3179983
EP3506710
IL250568
IN201727005511
JP2017528516
JP3025010
JP3031712
JP3031852
KR1020170041769
MX2017001971
RU0002697851
RU2017106896
Latest bibliographic data on file with the International Bureau
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